Description
IL-1 beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1 beta is required for tumor growth, metastasis, and angiogenesis in several animal models.
Recombinant protein corresponding to aa118-269 with a His-Tag from mouse Interleukin 1 beta, expressed in E. coli. Purified by using conventional chromatography techniques